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M9650967.TXT
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1996-03-30
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Document 0967
DOCN M9650967
TI Intestinal histoplasmosis in AIDS patients: report of three cases
observed in France and review of the literature.
DT 9505
AU Trylesinski A; Carbonnel F; Bouchaud O; Beaugerie L; Gharakanian S;
Rozenbaum W; Cosnes J; Gendre JP; Le Quintrec Y; Service de
Gastroenterologie et de Nutrition, Hopital; Rothschild, Paris, France.
SO Eur J Gastroenterol Hepatol. 1995 Jul;7(7):679-83. Unique Identifier :
AIDSLINE MED/96022534
AB We report three cases of colonic histoplasmosis observed in a
non-endemic area in patients with AIDS. The patients presented with
fever, abdominal pain and an abdominal mass in the right lower quadrant.
Diagnosis was obtained using Gomori-Crocott staining of endoscopic or
surgical biopsies. One patient died without specific treatment and two
patients had a complete remission when treated with intravenous
amphotericin B but suffered a relapse when given oral itraconazole.
Thus, physicians in areas where intestinal histoplasmosis is not endemic
should be aware of the condition. Diagnosis can easily be obtained using
Gomori-Crocott staining of colonoscopic biopsies; this should avoid
unnecessary laparotomies and allow specific treatment to be instituted
rapidly.
DE Adult Amphotericin B/THERAPEUTIC USE Antibiotics,
Antifungal/THERAPEUTIC USE AIDS-Related Opportunistic
Infections/DIAGNOSIS/DRUG THERAPY/ *EPIDEMIOLOGY/MICROBIOLOGY Case
Report Colonic Diseases/DIAGNOSIS/DRUG THERAPY/EPIDEMIOLOGY/
*MICROBIOLOGY Female France/EPIDEMIOLOGY
Histoplasmosis/DIAGNOSIS/DRUG THERAPY/*EPIDEMIOLOGY Human Male
JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).